Targeting cholesterol-dependent Piezo1 activation impairs amoeboid migration in melanoma cells
SignificanceThis study builds on a phenotypic drug screen that identified statins as inhibitors of bleb-based migration, a key mode of cancer cell movement through confined spaces. We show that statins reduce membrane cholesterol, disrupting the function ...
FedGuide: Diffusion Prior Alignment and Value Baseline Guidance for Heterogeneous Federated Reinforcement Learning
Beyond the Previous Layer: Residual Predictive Structure in Sparse MoE Routing
Colla-Q: Toward Collaborative Experts in MoE Quantization via Minimax Precision Balancing
T-SANDHI: Tone Sandhi-aware Adaptive Network with Decoupled Hybrid Injection for Low-resource Taiwanese Hokkien Speech Recognition
Higher-order pruning of experts in mixture-of-experts language models
Generalist-Specialist Mixture-of-Experts for Rare Pathology Detection in Multimodal Imaging
MoRE: Mixture of Reused Experts
Infinite-Parameter LLMs: Generating and Adapting Weights from Live Data
The Other Half of the Memory Wall: Serving 35B MoEs from SSD with Trained Routing Prediction
National Guacamole Day 2026 deals: Score free food from Qdoba, Del Taco, Tabanero, and more

It feels like there's a new food celebration every week. We're not complaining. We didn't celebrate National French Fry Day and National Hot Dog Day, but we know that a lot of people do. And smart people celebrate by taking advantage of promotions offered by leading retailers during these events.
National Guacamole Day is no different. We can't say we had this date circled on our calendar, but many popular chains are offering limited-time deals and genuine giveaways to mark the occasion. This is where you can capitalize.
Sept. 16 is National Guacamole Day. We're seeing special offers go live at Qdoba, Del Taco, Tijuana Flats, and more. We've lined up our favorites below so you can eat for free (or at a heavily reduced rate) today.
Bubbakoo’s Burritos
Free chips and a 4-ounce guac with any entree purchase.
California Tortilla
Free guac and chips with any entree purchase.
Cocina 214
Score discounted guacamole all day on Sept. 16.
Del Taco
Rewards members can score an Epic Fresh Guacamole Burrito for $5 (online or in app).
Fuzzy’s Taco Shop
Free chips and guacamole with an in-app purchase of $5 or more with code GUACDAY.
Guzman y Gomez
Get free guacamole added to your main menu item.
Moe’s Southwest Grill
Score free guac with any entree purchase.
Moxies
Get fresh Smashed Guacamole with Tajín-seasoned chips for $12 during Happy Hour.
Qdoba Mexican Eats
Score free regular chips and guac when you make any entree purchase and enter code GUACDAY (online or in app).
Tabanero
Save 20% on your online order when you enter promo code GUAC20 during checkout.
Tocaya Modern Mexican
Rewards members can get a free half-size chips and guac with a purchase of $15 or more.
OPPO ColorOS 17 发布:全新“流体设计”、新一代小布
IT之家 9 月 17 日消息,在今日的 OPPO ColorOS 17 发布暨开发者大会上,ColorOS 17 正式发布,口号为“超流畅,更懂你”。

ColorOS 17 的流畅双引擎迎来全面升级:极光引擎从绘制层深入渲染层,实现融合渲染,内存占用和渲染负载降低;潮汐引擎通过个性化行为感知链实现精准调度,带来行业首个记忆后台。

ColorOS 17 采用“流体设计”,带来凝光视效、流体动效、柔性反馈,比如拖动音乐播放器进度条,会有光影变化。









性能优化方面,ColorOS 17 带来个性化感知调度,官方称之为“记忆后台”,前台应用性能前倾、重要后台应用精准保活、非重要后台智能冷存,后台稳定保活率提升 55.6%。
此外,相册选图、小程序启动、应用内跳转等高频场景均实现秒加载、秒启动、秒跳转。





ColorOS 17 是迈向个性化主动智能的关键一步,On-Device Compute 端侧大模型、Persona X 记忆共生引擎、Agent Matrix 智能体生态框架,三大 AI 技术底座也迎来全面突破。
去年,OPPO 行业首创 AI 一键闪记,率先将个性化记忆体验带给用户,其首创的取餐码上线以来累计使用超 10 亿次,一年内已成系统标配。


今年,ColorOS 17 一键闪记在原有记码记账记视频,记大师参数的基础上,新增记取件码、记联系人信息、记演唱会抢票时间等场景。一键闪记可在任意界面结合当前内容给出意图推荐。


新一代小布支持更长的上下文对话,智能化能力也迎来升级;用户可自定义小布的情绪、表达风格、回复长度等。


目前,小布建议一站式主动生活服务已与 40+ 头部三方合作,覆盖 150+ 服务种类、700+ 服务场景。


小布来电功能可帮助用户避免错过重要行程,比如打车目的地和订票出发点不一致,小布会强提醒用户进行检查。



ColorOS 17 还联合地图 App 带来流体云融合导航功能,可在流体云通知部分显示导航指引,依托自研“蜂群感知技术”,实现微观区域高精度感知,播报准确率达 95%。
此外,用户坐地铁时,流体云融合导航会显示每个城市地铁口的图案(夜间地铁口会亮灯),以及附近的地标建筑图案。









在影像上,ColorOS 17 带来全新“AI 修图师”,自研达芬奇视觉理解大模型,通过六大专家模型保证照片真实自然。同时,它会基于图片的理解主动推荐修图建议,还能根据参考图进行复刻。


ColorOS 17 推出“AI 笔记”,打造一站式个人知识管理空间。支持写作、录音、拍照扫描、视频链接导入、文件文档导入、小布记忆导入等丰富记录方式;用户还能通过 AI 笔记助手,用自然语言随时调整内容,同步生成结构化信息速览图,还能
Unifying Semantic Priors and High-Frequency Traces: Enhancing V-JEPA with Mixture-of-Experts for Robust Synthetic Image Forensics
Which Pretext Task Transfers? Self-Supervised Pretraining Objectives for Lung Ultrasound
What Breaks Under Pruning in Smart Homes, and When? Evaluating LLM Degradation Across Architectures and Task Complexity
PopSockets expands popular Low-Pro line with new 3-in-1 iPhone cases

PopSockets just launched the Low-Pro Case, a new line of MagSafe iPhone cases and the first expansion of its Low-Pro line. The three-in-one MagSafe case supports wireless charging and also includes a collapsible Low-Pro Grip and a built-in phone stand.
Earlier this year (June 16, to be exact), PopSockets launched its Low-Pro Grip — a series of ultra-thin magnetic grips designed to lie flush against the back of your phone — exclusively in Apple stores. The Low-Pro Grip is just 2.6 mm when collapsed, and PopSockets says the launch received tons of positive feedback (most likely from people like me who can't stand when things are even a little bit off). PopSockets founder David Barnet told Mashable the Low-Pro is the brand's most popular new launch since the company's earliest days.
So, naturally, the company is taking the concept further by embedding that same disappearing grip directly into a protective phone case. According to PopSockets, the new Low-Pro Case offers:
Integrated Low-Pro Grip
Adjustable stand for both portrait and landscape viewing
10-foot drop and 360-degree phone protection
Optimized for MagSafe cases
Wireless charging (meaning the phone charges wirelessly through the case and grip)
Here's what the new case looks like in practice:
And here's how it works: instead of snapping an accessory onto your existing phone case, this is a grip and case in one. It uses a flexible unibody design with a built-in grip that expands when you need to hold your phone, then collapses flat when you slide it into your pocket. It also has a metal ring that functions as a phone stand.
Launching Sept. 15 for $59.99, the new PopSockets Low-Pro Case is available for the iPhone 17 Pro and Pro Max as well as the newly announced iPhone 18 Pro and iPhone 18 Pro Max (the Low-Pro Grip costs $39.99 on its own). For now, it comes in black and burgundy and is available for sale on Amazon, Best Buy, and the PopSockets website.
Our tech editor demoed the new case in person with Barnett and can confirm that the grip is "extraordinarily thin." While it might feel a bit flimsy due to the ultra-thin, flexible parts, Barnett says they tested the grip and found it could support over 40 pounds. The company discovered this fact in a very scientific "Fanta test," as you can see in this TikTok: